Yes, it’s way early. But here’s some thoughts from “2022 Senate Races: Initial Ratings” by J. Miles Coleman at Sabato’s Crystal Ball:

“Republicans will be defending more Senate seats than Democrats in 2022, but both sides have some potential pickup opportunities — though a large gain for either party seems unlikely….Sen. Rob Portman (R-OH) would have been an overwhelming favorite to win a third term, but even with his retirement, Ohio’s rightward lean makes it an uphill climb for Democrats….Democrats’ clearest path to gaining seats runs primarily though the Rust Belt, as Pennsylvania and Wisconsin seem to be their top offensive races, though they may finally get lucky in North Carolina….We rate four states — Arizona, Georgia, Nevada, and New Hampshire — as Leans Democratic, and these seem to be the most obvious GOP targets….There will likely be more retirements this cycle, but they probably won’t change the fundamental picture.”

Here’s Crystal Ball’s first 2022 Senate race ratings map:

The wild card in fleshing out strategy for Democrats has to be the applicability of the lessons of Georgia’s double Senate flip for Democratic Senate campaigns in other states? It’s a question that should be thoroughly investigated by the DSCC and every Democratic Senate campaign for 2022.